Environmentally Relevant Concentrations of Triclosan Induce Cyto-Genotoxicity and Biochemical Alterations in the Hatchlings of Labeo rohita

Xenobiotic Triclosan (TCS) is of great concern because its existence in a variety personal, household and healthcare products continuous discharge water worldwide. Excessive use TCS-containing sanitizers antiseptic during the COVID-19 pandemic further increased content aquatic ecosystems. The present study deals with cyto-genotoxic effects biochemical alterations hatchlings Labeo rohita on exposure to environmentally relevant concentrations TCS. Three-days-old were exposed tap water, acetone (solvent control) 4 (6.3, 12.6, 25.2 60 µg/L) TCS for 14 days kept recovery period 10 days. significant concentration-dependent decline cell viability but increase micronucleated cells, nucleo-cellular abnormalities (NCAs) DNA damage parameters like tail length, moment, olive moment percent after persisted till end period. Glucose, triglycerides, cholesterol, total protein, albumin, bilirubin, uric acid urea (except an at showed (p ? 0.05) decrease exposure. same trend albumin bilirubin) continued post In comparison control, transaminases (alanine aspartate aminotransferases) as well period, while alkaline phosphatase was followed by results show that cause deleterious L. rohita.